Description
Product Characteristics:
Aliases: CFHL antibody, CFHL1 antibody, CFHL1P antibody, CFHR1 antibody, CFHR1P antibody, Complement factor H related 1 antibody, Complement factor H related 1 pseudogene antibody, Complement factor H related protein 1 precursor antibody, Complement factor H-related protein 1 antibody, FHR 1 antibody, FHR-1 antibody, FHR1 antibody, FHR1_HUMAN antibody, H factor (complement) like 1 antibody, H factor (complement) like 2 antibody, H factor like protein 1 antibody, H factor-like protein 1 antibody, H-factor-like 1 antibody, H36 1 antibody, H36 2 antibody, H36 antibody, HFL1 antibody, HFL2 antibody, MGC104329 antibody
Target Information: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]